Molecular Biomechanics
Date/Time: | Monday, 16 Apr 2012 from 4:00 pm to 4:50 pm |
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Location: | Physics Hall Room 5 |
Phone: | 515-294-5441 |
Channel: | College of Liberal Arts and Sciences |
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Abstract
Molecular mechanics studies mechanics of biomolecules and uses mechanics to study biology at the molecular level. Mechanical factors can cause and/or regulate molecular deformation, conformational change, and receptor-ligand binding/unbinding. In this talk, Dr. Cheng Zhu will show three examples from the work of his laboratory: 1)Measurements of molecular stiffness and use of stiffness measurements to determine molecular conformation; 2)Visualization of conformational changes of single molecules on living cells in real-time and their impact on function; and 3)Biophysical regulation of receptor-ligand kinetics.