Molecular Biomechanics

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Date/Time:Monday, 16 Apr 2012 from 4:00 pm to 4:50 pm
Location:Physics Hall Room 5
Phone:515-294-5441
Channel:Colloquium
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Dr. Cheng Zhu (Georgia Tech)

Abstract

Molecular mechanics studies mechanics of biomolecules and uses mechanics to study biology at the molecular level. Mechanical factors can cause and/or regulate molecular deformation, conformational change, and receptor-ligand binding/unbinding. In this talk, Dr. Cheng Zhu will show three examples from the work of his laboratory: 1)Measurements of molecular stiffness and use of stiffness measurements to determine molecular conformation; 2)Visualization of conformational changes of single molecules on living cells in real-time and their impact on function; and 3)Biophysical regulation of receptor-ligand kinetics.