How Electron Cryotomography is Opening a New Window into Microbial Ultrastructure

«   »
Su Mo Tu We Th Fr Sa
28 29 30 1 2 3 4
5 6 7 8 9 10 11
12 13 14 15 16 17 18
19 20 21 22 23 24 25
26 27 28 29 30 31 1
Date/Time:Monday, 15 Oct 2012 from 4:10 pm to 5:00 pm
Location:Physics 0005
Phone:515-294-5441
Channel:Colloquium
Actions:Download iCal/vCal | Email Reminder
Grant Jensen (Caltech, HHMI)

Electron cryotomography (ECT) is an emerging technology that allows small cells to be imaged in 3-D in an intact, near-native state to "molecular" (5-2 nm) resolution. The basic principles of ECT will be explained as well as its future promises and limitations. Example results that have helped us understand the structural biology/biophysics of microbial cell shape determination, motility, chemotaxis, division, and interspecies attack will be shown.