Dynamic Sensing at the Nanoscale with DNA

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Date/Time:Monday, 24 Oct 2016 from 4:10 pm to 5:00 pm
Location:Phys 0003
Contact:
Phone:515-294-5441
Channel:College of Liberal Arts and Sciences
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Michael Poirier, Ohio State University

Abstract

Nanoscale mechanical devices with controllable motion are essential for applications in sensing, molecular robotics, nanomaterials and nanomanufacturing. DNA nanotechnology has revolutionized the engineering of complex nanostructures. However, the development of dynamic nanostructures that carry out defined functions is only beginning to be explored. In this talk, I will provide an overview of the DNA nanotechnology field, including current successes and challenges, and then discuss our recent work on developing nanodynamic devices for measuring molecular scale forces and mesoscopic structural dynamics of nucleosomes, the fundamental building block of the human genome.

Bio

Dr. Michael Poirier is a Professor in the Department of Physics at the Ohio State University. He also has a courtesy Professor appointment in the Department of Chemistry & Biochemistry at the Ohio State University. Honors include the Burroughs Wellcome Fund Career Award in Basic Biomedical Sciences in 2005, the Ruth L. Kirschstein National Research Service Award, Individual Fellowship, National Institutes of Health in 2004; and the 2003 Postdoctoral Award from Le Centre National de Recherche Scientifique, France.

He is author of more than 43 publications; 21 corresponding author publications*; 11 first author publications; 1411 citations; h-index 22, i10-index 32. (Stats from Google Scholar). He is a 2015 Reviewer for the NSF, MCB, Genetic Mechanisms; a 2016 Ad hoc member of Molecular Genetics A NIH Study Section; and 2016-2020 Member of Molecular Genetic A NIH Study Section.